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A Methylphenidate, RITALIN, is methylphenidate. It.


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Methylphenidate (methylphenidatum, meridil, centedrin, centedrin, ritalin, rilatine, methylphenidati hydrochloridum, methylphenidate hydrochloride) is a non-amphetamine psychostimulant. Psychiatrists have been using this drug for over 40 years, they and pharmacologists did not know then, and do not know now, how and why it works.

In 1944, methylphenidate was synthesized.
In 1961, doctors from around the United States drew attention to the fact that the new generation drugs of the CNS stimulant group methylphenidate and dextroamphetamine helped children with Attention Deficit Hyperactivity Disorder (ADHD), but compared with benzedrine, they caused much less side effects. After that, Ciba-Geigy proposed the use of Ritalin (methylphenidate) for the treatment of this disease. The drug was initially rejected by the US Food and Drug Administration (FDA), but was then approved for this indication in 1963.

According to the US Drug Enforcement Administration, street abuse of methylphenidate has become a serious problem. Introduced into American schools in the 1960s, the drug now costs between $10 and $15 a dose for drug traffickers, although no clandestine lab production has been recorded. The United States consumes 85% of the total production of methylphenidate (Ritalin).

In 2002, the Parliamentary Assembly of the Council of Europe noted the high level of legal consumption of methylphenidate in Belgium, Germany, Iceland, Luxembourg, the Netherlands, Switzerland and the United Kingdom. The number of British children prescribed stimulants increased by 9200% between 1992 and 2000, while in Australia the number of prescriptions for stimulants for children increased 34-fold over the past 20 years. In France, between 1989 and 2002, the number of children diagnosed with hyperactivity increased by 600%. In Mexico, sales of methylphenidate jumped 800% between 1993 and 2001.

In medicine:
The drug has limited use as a psychostimulant in asthenic conditions, increased fatigue. It can be used for depression of the nervous system caused by antipsychotic drugs, narcolepsy. Also prescribed to treat attention deficit disorder, activity disorder, depression.

Pharmaceutical tablets are most commonly taken by mouth or crushed and sniffed as a powder. However, some drug addicts dissolve the tablets in water and inject the liquid inside.
By action, methylphenidate is close to amphetamine, but has a less strong stimulating effect and has less effect on peripheral adrenergic systems; does not cause a pronounced increase in blood pressure. Suppresses appetite, causes wakefulness, increases concentration and attentiveness, euphoria.

Side effects are possible: insomnia, nausea, sometimes agitation and anxiety, exacerbation of psychopathological symptoms. Addictive.

Complications arising from the use of methylphenidate are due to the insoluble excipients used in the tablets. When injected, these materials block small blood vessels, causing serious damage to the lungs and retina. Methylphenidate also produces an increase in heart rate and blood pressure levels due to high doses, and can lead to serious psychological dependence.
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